Gholamreza Bahrami

Personal Information:

First name :      Gholamreza                             Sure name:  Bahrami

Date of Birth:  Feb.20,1961                             Nationality: Iranian

Gender: Male

Home Address:    

Home phone Number:  ± 0098 0831 8350197

Academic Degree: Professor of Pharmacology

h-index= 18

Education:

1984- 1989                           Pharm. D in Pharmacy , School of Pharmacy, Isfahan University of Medical Sciences  Isfahan, IRAN

1989-1993                            Ph.D in Pharmacology , School of Pharmacy, Isfahan University of Medical Sciences  Isfahan, IRAN

Work  Experience :

1993 - Present                     Faculty Member, Medical School, Kermanshah University         of Medical Sciences and Health services (KUMS), Kermanshah, IRAN

Publications (English):

Books:

Bahrami G, Trans and other fatty acids: Effects on endothelial functions. In: R.W. Watson et al. Fatty Acids in Health Promotion and Disease Causation. American Oil chemist association press,  2009

Patents:

Herbal extract composition for the treatment of diabetes and a method of extracting the same.   US 9296831 B2,   Publication date:                Mar 29, 2016

Journals:

1)     

Ali Fattahi, Fatemeh Niyazi, Behzad Shahbazi, Mohammad Hosein Farzaei, Gholamreza Bahrami . Antidiabetic mechanisms of Rosa canina fruits: An in vitro evaluation . Journal of Evidence-Based Complementary & Alternative Medicine. 2016 Jun 26.

2)     

Mohammad Taher Bahrami, Bahareh Mohammadi, Shahram Miraghaei, Atefeh Babaei, Matin Ghaheri, Gholamreza Bahrami*. Quantification of sofosbuvir in human serum by liquid chromatography-negative ionization mass spectrometry using the parent peak and its source-induced fragment; Application to a bioequivalence study. Journal of Separation Sciences. 2016 Jul;39(14):

3)     

Mohammad Reza Saidi,Mohammad Hosein Farzaei, Shahram Miraghaee, Atefeh Babaei,Bahareh Mohammadi, Mohammad Taher Bahrami, Gholamreza Bahrami, Antihyperlipidemic Effect of Syrian Mesquite (Prosopis farcta) Root in High Cholesterol Diet–Fed Rabbits. Journal of Evidence-Based Complementary & Alternative Medicine 2016 Oct;21(4)

4)     

Mohammad Bagher Gholivand, Mehdi Khodadadian & Gholamreza Bahrami. Molecularly Imprinted Polymer Preconcentration and Flow Injection Amperometric Determination of 4-Nitrophenol in Water. Analytical Letters, 48: 2856–2869, 2015

5)     

Mehdi Khodadadian^a,*, Ronak Jalili^a, and Gholamreza Bahrami^a. Adsorptive behavior and voltammetric determination of hydralazine hydrochloride at a glassy carbon electrode modified with multiwalled carbon nanotubes  I.J.P.R  In press

6)     

 Shahlaei M, Bahrami G, Abdolmaleki S, Sadrjavadi K, Majnooni MB Application of unfolded principal component analysis-radial basis function neural network for determination of celecoxib in human serum by three-dimensional excitation-emission matrix fluorescence spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Mar 5;138:675-83. doi: 10.1016/j.saa.2014.12.007. Epub 2014 Dec 8.

7)     

 Gholamreza Bahrami, Soheila Bahrami, Mohammad Taher Bahrami, Yahya Pasdar, Mansour Rezaei, Mitra Darbandi  The Trans Fatty Acid Content of Snacks Offered in Kermanshah International Journal of Health and Life Sciences

8)     

 Taheri S¹, Jalali F, Fattahi N, Bahrami G. Sensitive determination of atorvastatin in human plasma by dispersive liquid-liquid microextraction and solidification of floating organic drop followed by high-performance liquid chromatography. J Sep Sci. 2015 Jun;38(2):309-15.

9)     

Taheri S¹, Jalali F¹, Fattahi N², Jalili R³, Bahrami G^3. Sensitive determination of methadone in human serum and urine by dispersive liquid-liquid microextraction based on the solidification of a floating organic droplet followed by HPLC-UV. J Sep Sci. 2015 Oct;38(20):3545-51.

10)     M.B. Majnooni1, A. Mohammadi-Farani2,*, M.B. Gholivand3, M.R. Nikbakht2 and

G.R. Bahrami1,2 Chemical composition and anxiolytic evaluation of Achillea Wilhelmsii

C. Koch essential oil in rat Research in Pharmaceutical Sciences, November 2013; 8(4): 269-275

11)  

Bahareh Mohammadi 1&2, Esmail Tammari2, Sajad Fakhri3, Gholamreza Bahrami

Applicability of LC-MS/MS to optimize derivatization of topiramate with FMOC-Cl using reacted/intact drug ratio Journal of Chromatography B (2013)

12)  

Bahareh Mohammadi1, Mohammadbagher Majnooni1*, Nazanin-sadat Afnanzade2, Ronak jalili and Gholamreza Bahrami1,2  Simple and rapid ultra high performance liquid chromatographic (UHPLC) method for the determination of levetiracetam in human serum: Application to a bioequivalence study. African Journal of Pharmacy and Pharmacology Vol. 6(27). 2017-2022, July, (2012)

13)  

M. B. MAJNOONI, B. MOHAMMADI*, R. JALILI AND G. H. BAHRAMI  Rapid and Sensitive High Performance LiquidChromatographic Determination of Zonisamide inHuman Serum Application to a Pharmacokinetic Study. Indian Journal of Pharmaceutical Sciences July - August( 2012 )360-364

14)   Nima Sanadgol1, Ali Mostafaie2, Kamran Mansouri2, Gholamreza Bahrami2 Effect of palmitic acid and linoleic acid on expression of ICAM-1 and VCAM-1 in human bone marrow endothelial cells (HBMECs) Arch Med Sci 2, April  2012 192-8

15)  

Bahareh Mohammad¹, Mohammad Bagher Majnooni, Pyman Malek Khatabi ,Ronak jalili Gholamreza Bahrami.* 9-Fluorenylmethyl chloroformate as a fluorescence-labeling reagent for derivatization of carboxylic acid moiety of sodium valproate using liquid chromatography/tandem mass spectrometry for binding characterization: A human  pharmacokinetic study. Journal of Chromatography B,(2012) 12-18

16)  

Leila Hosseinzadeh, Javad Behravan, Fatemeh Mosaffa, Gholamreza Bahrami, Ahmadreza Bahrami,  Gholamreza Karimi.  Effect of Curcumin on Doxorubicin-induced Cytotoxicity in H9c2 Cardiomyoblast Cells  Iranian Journal of Basic Medical Sciences  Vol. 14, No. 1, Jan-Feb 2011, 49-56  .

17)    Leila Hosseinzadeh, Javad Behravan, Fatemeh Mosaffa, Gholamreza Bahrami, Ahmadreza Bahrami,  Gholamreza Karimi.  Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species. Food and Chemical Toxicology 49 (2011) 1102–1109

18)   Jalali;Ahmadi;Roushani;Bahrami;Shamsipur; Amperometric Determination of Cholesterol-Reducing Drug,Ezetimibe, Using Glassy Carbon Electrode Modified with Multiwalled Carbon Nanotubes and Sodium Dodecylsulfate Analyt. Lett. 43: 1481–1490, 2010

19)  

 Gholamreza Bahrami, Bahareh Mohammadi, Pyman Malek Khatabi, Mohammad Hosein Farzaei, Mohammad Bagher Majnooni, Saba Rahimi Bahoosh. Application of one-step liquid chromatography–electrospray tandem MS/MS and collision-induced dissociation to quantification of ezetimibe and identification of its glucuronated metabolite in human serum: A pharmacokinetic study. Journal of Chromatography B, 878 (2010) 2789–2795

20)  

Nima Sanadgo, Ali Mostafaie, Gholamreza Bahrami^b, Kamran Mansouri, Fariba Ghanbari and Ali Bidmeshkipour Elaidic acid sustains LPS and TNF-α induced ICAM-1 and VCAM-I expression on human bone marrow endothelial cells (HBMEC) Clin. Biochem. 2010. In press 

21)  

Gholivand, M.B., Khodadadian, M., Majnooni, M.B., Bahrami, G Electroreduction of zonisamide at hanging mercury drop electrode and its determination in pharmaceutical formulations and spiked human serum samples  Analyt. Lett. 43 (2), 2010. pp. 269-279

22)  

Nemati, H., Bahrami, G., Rahimi, Z.  Rapid separation of human globin chains in normal and thalassemia patients by RP-HPLC Mol Biol Rep (2011) 38:3213–3218

23)  

Nemati, H., Rahimi, Z., Bahrami, G.  The Xmn1 polymorphic site 5′ to the Gγ gene and its correlation to the Gγ:Aγ ratio, age at first blood transfusion and clinical features in β-Thalassemia patients from Western Iran Molecul. Biol.  Reports 37 (1), 2010. pp. 159-164

24)  

Bahrami, G., Mohammadi, B., Farshchi, A., Ghiasi, G. Quantitative analysis of sertraline in human serum by LC with fluorescence detection after pre-column derivatization with 4-chloro-7-nitrobenzofurazan  Chromatographia 70 (1-2), 2009. 323-327

25)  

Bahrami, G. Mohammadi,B.  Enhancement of fluorescence intensity of tramadol and its main metabolites in high-performance liquid chromatography using pre-column derivatization with 9-Fluorenylmethyl chloroformate  Chromatographia a 68 (11-12) 2008,  935-940

26)  

Bahrami, G. Piravi.Vanak, Z. Improvement of fatty acids composition and reduction of cholesterol contents in traditionally prepared butter and oil in west of Iran. Arya Atherosclerosis Journal. 2009.

27)  

 Bahrami, G ,  Masoumi M,  Rahimi Z.  Co-existence of fatty acids changes in aorta artery and adipose tissue; comparison between CAD and non CAD patients. J Thromb Thrombolysis. 27 (2), (2009)  185-190

28)  

Bahrami, G. Mohammadi,B.  Determination of oseltamivir carboxylic acid in human serum by solid phase extraction and high performance liquid chromatography with UV detection.  ; J Chromatogr B Analyt Technol Biomed Life Sci. Volume 864, Issues 1-2, 15 March 2008, Pages 38-42

29)  

Bahrami, G. Mohammadi,B.  High performance liquid chromatographic determination of inactive carboxylic acid metabolite of clopidogrel in human serum; application to a bioequivalence study.  J Chromatogr B Analyt Technol Biomed Life Sci. Volume 864, Issues 1-2, 15 March 2008, Pages 168-172

30)  

Fahimeh Jalali, Elham Arkan, and Gholamreza Bahrami . Preparation of a gabapentin potentiometric sensor and its application to pharmaceutical analysis.  Sensors and Actuators B: Chemical  2007 Aug; [Epub ahead of print]

31)  

Bahrami, G. Mohammadi,B.  Rapid and sensitive bioanalytical method for measurement of fluvoxamine in human serum using 4-chloro-7-nitrobenzofurazan as pre-column derivatization agent: Application to a human pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 1;857(2):322-6

32)  

 Bahrami, G. Mohammadi,B.  Determination of clarithromycin in human serum by high-performance liquid chromatography after pre-column derivatization with 9-fluorenylmethyl chloroformate: Application to a bioequivalence study J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):417-22.

33)  

  Bahrami, G. Mohammadi,B. A novel high sensitivity HPLC assay for topiramate, using 4-chloro-7-nitrobenzofurazan as pre-column fluorescence derivatizing agent. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):400-4

34)  

   Bahrami, G. Mohammadi,B.  An isocratic high performance liquid chromatographic method for quantification of mycophenolic acid and its glucuronide metabolite in human serum using liquid-liquid extraction: Application to human pharmacokinetic studies. Clin Chim Acta. 2006 Aug;370(1-2):185-90.

35)  

   Bahrami, G. Mohammadi,B.  Sensitive microanalysis of gabapentin by high-performance liquid chromatography in human serum using pre-column derivatization with 4-chloro-7-nitrobenzofurazan: Application to a bioequivalence study. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jun 6;837(1-2):24-8.

36)  

  Bahrami, G. Kiani,A.  Sensitive high-performance liquid chromatographic quantitation of gabapentin in human serum using liquid-liquid extraction and pre-column derivatization with 9-fluorenylmethyl chloroformate.
J Chromatogr B Analyt Technol Biomed Life Sci. 2006 May 1;835(1-2):123-6.

37)  

  Bahrami,G. Ghanbarian, E. Masoumi,M. Rahimi,Z. Rezwanmadani,F. Comparison of fatty acid profiles of aorta and internal mammary arteries in patients with coronary artery disease. Clin Chim Acta. 2006 Aug;370(1-2):143-6.

38)  

 Bahrami, G. Mirzaeei, Sh. Kiani, A. A rapid high performance liquid chromatographic determination of methyldopa in human serum with fluorescence detection and alumina extraction: application to a bioequivalence study.
J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Mar 7;832(2):197-201 

39)  

   Jalali,F. Rajabi, MJ. Bahrami, G. Shamsipur,M.  Preparation of a novel iodide-selective electrode based on iodide-miconazole ion-pair and its application to pharmaceutical analysis. Anal Sci. 2005 Dec;21(12):1533-5.

40)  

Bahrami, G. Mohammadi, A.  A new on-line, in-tube pre-column derivatization technique for high performance liquid chromatographic determination of azithromycin in human serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jan 18;830(2):355-8. Epub 2005 Nov 23

41)  

Bahrami, G. Mohammadi, A. Mirzaeei, Sh. Kiani, A. Determination of atorvastatin in human serum by reversed-phase high-performance liquid chromatography with UV detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Nov 5;826(1-2):41-5.

42)  

 Bahrami, G. Mirzaeei, Sh. Kiani, A. Mohammadi, B. High-performance liquid chromatographic determination of lamivudine in human serum using liquid-liquid extraction; application to pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Sep 5;823(2):213-7.

43)  

Bahrami, G. Mirzaeei, Sh. Mohammadi, B. Kiani. High performance liquid chromatographic determination of topiramate in human serum using UV detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Aug 5;822(1-2):322-5.

44)  

Bahrami, G. Mirzaeei, Sh. Mohammadi, B. Kiani. High performance liquid chromatographic determination of azithromycin in serum using fluorescence detection and its application in human pharmacokinetic studies.J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jun 25;820(2):277-81.

45)  

Bahrami, G. Rahimi, Z. Fatty acid composition of human milk in Western Iran. Eur J Clin Nutr. 2005 Apr;59(4):494-7.

46)  

 Bahrami, G. Mirzaeei, Sh. Kiani, A. Determination of acyclovir in human serum by high-performance liquid chromatography using liquid-liquid extraction and its application in pharmacokinetic studies.J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Feb 25;816(1-2):327-31.

47)  

 Bahrami, G. Mirzaeei, Sh. Kiani, A.Sensitive analytical method for Topiramate in human serum by HPLC with pre-column fluorescent derivatization and its application in human pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Dec 25;813(1-2):175-80.

48)  

 Bahrami, G. Mirzaeei, Sh.,Simple and rapid HPLC method for determination of amlodipine in human serum with fluorescence detection and its use in pharmacokinetic studies. J Pharm Biomed Anal. 2004 Sep 21;36(1):163-8.

49)  

Bahrami, G. Mirzaeei, Sh.  Determination of trans fatty acid content in commertially manufactured hydrogenated oils and margarine in Iran. Ir. Heart J. Fall 4 (2003) 59-67

50)  

 Shirazi FH, Bahrami G, Stewart DJ, Tomiak E, Delorme F, Noel D, Goel R.A rapid reversed phase high performance liquid chromatographic method for determination of etoposide (VP-16) in human plasma. J Pharm Biomed Anal. 2001 Jun;25(3-4):353-6.

51)  

 Ghafghazi,T. Bahrami,G. The use of whole saliva for bioavailability studies of diphenylhydantoinin normal subjects. Ir.J.Med Sci.16,(1991)162

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