PERSONAL:
Name: Farhad Oubari
Title: Msc of Hematology (Researcher)
Date of Birth: 21/09/1978
Nationality: Iranian
Office address: Department of Stem cell and Leukemia ,Medical Biology Research Center &
Department of Laboratory Sciences ,Paramedical Faculty , Kermanshah University
of Medical Sceinces, Kermanshah , Iran.
E-mail:Farhadobari@yahoo.com & Foubari@mbrc.ac.ir
Tel: + 98 (83) 34243452
Fax: + 98 (83)
34210365
Cell Phone:+98 0918 130 7527
EDUCATION:
Degree
Institute
1.Msc in hematology
Blood Transfusion Research Center, High Institute for
Tehran, Iran Research and Education in
Transfusion Medicine.
2.BSc in Laboratory Department of Laboratory
Sciences, Shiraz University
Sciences, Shiraz, Iran of Medical Sciences
Employment:
1. Molecular
Genetic & Cell Culture (Medical
Biology Research Center)
2. Research Center of Bone Marrow Transplantation , Flow
cytometry lab (Kermanshah
University of
Medical Sciences), Kermanshah-Iran
3.Department of laboratory Sciences, Para medical Faculty,
Kermanshah University
of Medical
Sciences, Kermanshah- Iran
4.Department of
Stem Cells &Blood Malignancies (Medical Biology Research Center)
5. Blood Transfusion Research Center(Stem Cell), High Institute for
Research and Education in Transfusion Medicine,Tehran,Iran.
Relevent course:
Title Center
Date
1.Hematology
courses Shiraz University of medical
Sciences
2003-2005
2. Practical
hematology Shiraz University of
medical Sciences
2003- 2005
3. Flow cytometry
Iranian Blood Transfusion Organization 2010 - 2013
4.Hemtology courses
Iranian Blood Transfusion Organization 2010-2013
5. Practical Hematology
Iranian Blood Transfusion Organization 2010-2013
6.Immunohematology course
Iranian Blood Transfusion Organization 2010-2013
Awards & merits:
1.
Selected as the
best employee in 2003-2004
WORK EXPERIENCE:
1. Immunophenotyping of leukemia and immunodeficiency patients
by flowcytometry
2. DNA analysis of leukemia and solid tumors
3. Cord Blood processing and
banking
4 .Work in Medical Laboratories
5 . PCR
6. Real Time –
PCR
7. Flowcytometry
8.Cell Culture
9.Western- blotting & Northern
blotting
10. RFLP
11. ELISA
12. Mesenchymal
stem cell Separation and expansion (Culture)
13. Hematopoietic stem cell
Separation and expansion (Culture)
14. Co culture
15.MTT assay and viability test
16.Computer Skills
17. Skills in diagnosis of hematologic
malignancies
18.Primer Design
19.Immunohistochymical staining such as (Perl’s Stain ,MPO, …)
PUBLICATIONS:
1.Farhad Oubari,Naser Amirizadeh, Hemen
Mohammadpour, Mozhdeh Nakhlestani, Mahin Nikougoftar Zarif. The important role of Flt3-l in exvivo
expansion of hematopoietic stem cells following co-culture with mesenchymal
stem cells. Cell Journal, 2015, Vol 17,No 2.
2. Oubari
F, Nikougoftar Zarif M, Amirizadeh N, Shaiegan M, Atarodi K, Nakhlestani
M,Mirzamoradi M, Fadai R, Golzade Kh. Isolation
and expansion of Mesenchymal Stem Cells from placent, Sci J Iran Blood
Transfus Organ 2013; 10(3): 222-230.
3.Mohammad Reza Nikbakht , Mahin Nikougoftar Zarif ,Farhad Oubari(Corresponder
author) , Kamran Mansouri, Roghayeh Hosseinikia , Mahboobe Hosseinikia ,
Ahmad Tajeh miri . Mesenchymal Stem Cells Transplantation: Immunobiology,
Therapeutic Applications and Challenges- Review Article. Scientific Journal of Kurdistan
University of Medical Sciences Volume 20, Issue 3, 15 July 2015, Pages 113-139.
4. MR Nikbakht ,M Nikougoftar Zarif, R
Hosseinikia, K Mansouri, F Oubari(Corresponder author),A a Moghaddam,M Hosseinikia,A Tajehmiri.
Overview on Some of Gene Mutations and ChromosomalAberrations in Acute Myeloblastic Leukemias with Normal
and Abnormal Karyotypes(Accepted-Inpress). J Clin Res
Paramed Sci;2017.
5.Kamran
Mansouri,Farhad Oubari,Somayeh Shamllo, Parya Ahmadi,Mahboob Kashani. Coagulation
and Angiogenesis in Cancer . J Clin Res Paramed Sci 2016; 5(1):142-154 .
6. Abbas Mohammadi , Ebrahim Abbasi Oshaghi , Arash Noori Sorkhani , Farhad
Oubari , Roghaye Hosseini Kia , Ali Rezaei. Effect of Opium on Lipid
Profile and Expression of Liver X Receptor Alpha (LXRα) in Normolipidemic Mouse,
Food and Nutrition Sciences , 2012,3,249-254.
7.Hossein Javad , Hosseinin- zijoud Seyed ,Oubari
Farhad , Mahmoodi Mehdi , Abbasi Oshaghi Ebrahim , Rajabi Gilan Nader ,
Ghasemi Seyed Ramin and Hashemi Behroz. Hepatoprotective effects of
hydroalcoholic extract of Allium
hirtifolium (Persian shallot) in diabetic rats,J Basic Clin Physical
pharmacol 2012;23(2):83-87.
8. Abbas Mohammadi , Nejad Mohammadi , Nader
Najafi , Kazem Hasanpoor , Ramezan Ali Taheri , Farhad oubari and Ebrahim Abbasi Oshaghi . Influence
of Flaxseed on Some Biochemical Factors , Antioxidant Activity and Expression
ABCG5 and ABCG8 Genes in the Liver of Diabetic Rat, British Journal of Medicine
& Medical Research , 4(18):3571-3580,2014.
9.Hemen Moradi – Sardareh , Nejad Mohammadi , Farhad
oubari , Mohammad Reza Nikbakht , Roghaye Hosseini Kia , Gholamreza
Farnoosh , Reza Yari, Fateme mirzaei and Kazem Hassanpour. Biomedical factors , MDA levels and Antioxidant activity
in Opium addicted Hamsters, International Reserch Journal of Biological
Sciences ,ISSN 2278-3202,Vol .3(2), 21-24,February (2014).
10.Abbas Mohammadi , Gholamreza Farnoosh , Roghaye Hosseini Kia , Farhad oubari , Kazem Hassanpour , Hemen Moradi-
Sardareh , Nejad Mohammadi , Ebrahim
Abbasi Oshaghi and Reza yari. The In
Vivo Biomedical and Oxidative Change by
Garlic and Ezetimibe Combination in Hypercholesterolemic Mice,International Research Journal of Biological
Sciences,2278-3202,Manuscript No:ISCA-IRJBS-2013-603.
11. E. Abbasi
oshaghi,, N. Zynolebadi, A. Mohammadi, M. Moradi, A. Tootoonchi, H.
Ghasemi, S. Hosseini-zijoud, F. Oubari, R. Hosseini kia, H.
Ghasemi1- Goodarzi. Oral opium reduced lipid profiles with change in
expression of liver x receptor alpha (LXRα). Research in Pharmaceutical
Sciences, 2012;7(5).
12.
Mahin Nikogoftar Zarif, Farhad Oubari. Micro
RNA Profiling of Megakaryocytic Differentiated Cord
Blood CD133+ Cells(Processing).
13. F.Oubari(Corresponder author), R , Hosseinikia , M.Hosseinikia. Immunomodulatory
Effects and Clinical Applications of Mesenchymal Stem Cells-Review Article.(Future
Medicine Meeting Abstracts)October 21-23 2015Vol.10 No.07s.
14. Ahmad Tajehmiri,Saeid Rahbar,Farhad Oubari.Probiotics
for Control of Nosocomial Infections.Biomedical Pharmacology
Journal,Vol.8No.1,2015.
15. Roghayeh Hosseinikia, Mohammad Reza Nikbakht,
Ali Asghar Moghadam, Ahmad Tajehmiri, Mahboobe Hosseinikia, Farhad Oubari(Corresponder
author), Mahin Nikougoftar Zarif, Yahya Pasdar, Kamran
Mansouri. Molecular and Cellular Interactions of
Allogenic and Autologus Mesenchymal Stem Cells with Innate and Acquired
Immunity and Their Role in Regenerative Medicine. IJHOSCR 11(1) -
ijhoscr.tums.ac.ir – January, 1, 2017.
16.
Nikbakht MR, Lachiniyan Sh, Rahbar S, Oubari F, Rostami Z and Tajehmiri
A. Aflatoxin M1 Contamination in Traditional Yoghurts Produced in Guilan
Province, Iran. Asian Journal of Pharmaceutical Research and Health
Care,2016 ; Vol 8(1), 1-3.
17. Hosseini Kia , Ghahramani L, salehi M, Oubari F,
Hosseinikia M, Kaveh M.H. Effect of a Healthy Nutrition Education Program on
Self-Efficacy in Dietary Behavior among Female Students of Guidance School in
Shiraz, Iran: Application of PRECEDE Model. Vol. 7, No. 5, Winter 2016,
Pages 499-509.
18. Hossinikia
R , Nikougoftar Zarif M, Pasdar Y, Haghnazari L , Hossinikia M ,Oubari F(Corresponder
author),. Biology , Labeling ,
Immunogenetic Isolation of Mesenchymal Stem Cells and Their role in Adult Stem
Cells Niche(Submitted –Under Review ).
19. Kardide B,
Oubari F , Mansouri K. Autophagy and its role in Cancer and Angiogenesis(In
Press).
20.Hosseinikia M,
Abdollahzadeh H, Oubari F, Hosseinikia R, Shabanpour M, Nachvak
MS. .Assessment of nutritional risk factor and SES indicator on childhood
cancer(Submitted –Under Review ).
21. Hosseinikia M,
Abdollahzadeh H, Oubari F, Hosseinikia R, Shabanpour M, Nachvak MS.Assessment
of qualitative and quantitative pattern of kebab intake as a potential
carcinogenic risk factor in Iranian adults(Submitted –Under Review ).
International Congresses (Oral &
Poster Presentation):
1. F . Obari , M.
Nikougoftar Zarif , N . Amirizade , K . Atarodi , M. Nakhlestani , H .
Mohammadpour , R. Hosseini Kia , M . Notghi , N . Razavi. FLT3-L ONLY IN CO
CULTURE MANNER IS AS
EFFECTIVE AS CYTOKINE
COCKTAILS FOR HEMATOPOIETIC STEM CELL
EXPANSION, WORD CORD BLOOD
CONGRESS AND INNOVATIVE THERAPIES FOR
SICKLE CELL DISEASE,
MONACO, OCTOBER 24-27, 2013.
2.Farhad Oubari(Corresponding –
Presenter (oral)), Mohammad reza Nikbakht , Roghaye Hosseni Kia , Hemn
Mohammadpour , Mahin Nikogoftar Zarif , Dariush Pormand , Fatemeh Darabi ,
Shahryar Aazimi , Mahbob Kashani.Expansion of umbilical cord blood
hematopoietic stem cell in co culture
with placental derived mesenchymal stem cell,6th International Iranian
Congress Labo ratory & Clinic.
3. Farhad Oubari (
Corresponding – Presenter (oral)), mahin Nikougoftar Zarif , Mohammad reza
Nikbakht, Roghaye Hosseni Kia, Fatemeh Darabi , Dariush Pormand , Mahbob
Kashani , Mahboobeh hosseini Kia ,
Shahriyar Aazimi. Isolation , expansion ,
osteogenic and adipogenic differentiation Mesenchymal Stem cells –
Derived from placenta, 6th
International Iranian Congress Laboratory
& Clinic.
4. Farhad Oubari (
Corresponding – Presenter( Poster)),Roghaye Hosseini kia , Ebrahim Abbasi
Oshaghi , Sajad obari, Mahboobe Hosseini Kia , Farzan Vafaee , Almas
jamshidi. Effect of Opium on Lipid
Profile and Expression of Liver X Receptor Alpha (LXRα) in Normolipidemic Mouse.5th
International &10th National Congress on Quality Improvement in Clinical
Laboratory, April 23-26,2012.
5. Farhad oubari (Corresponding- Presenter (Oral)) , , Dr.Mohammad Reza
Nikbakht, Roghayeh Hosseinikia Mahboobe Hosseinikia,Kamran mansouri. Stem
Cells Therapy and challenges ahead .Yasuj Blood Diseases International
Congress2015.
6. Farhad Oubari(Corresponding-Presenter (Poster)) ,
Mohammad Reza Nikbakht , Mahin Nikougoftar Zarif ,Roghayeh
Hosseinikia ,Mahboobe Hosseinikia ,Kamran Mansouri. In vitro Osteogenic and
Adipogenic Differentiation of Placenta- Derived Mesenchymal Stem Cells
(PD-MSCs). International Mashhadstemcell congress 2015.
7.Mohammadreza Nikbakht,Farhad Oubari,Ali asghar
Mogghadam,Roghayeh Hosseinikia,Mahboobe Hosseinikia.Effects of
Pharmaceutical Composition of All-Trans Retionoic Acid ,Valproic Acid and
5-Azacitidin in Patients with Acute Myeloid Leukemia Diagnosed in West of Iran.International
Congress of Physiology and
Pharmacology(Kashan2015).
8. Farhad Oubari(Corresponding Presenter(Poster),
Mohammadreza Nikbakht, Roghayeh Hosseinikia, Mahboobe Hosseinikia. Immunomodulatory
Effects and Clinical Applications of Mesenchymal Stem Cells- Review Article.International Congress of Regenerative
medicine Congress(Germany,Liepzing ,2015).
9. Oubari F , Hosseinikia R , Hosseinikia M .Expansion
of Umblical Hematopoietic
Stem Cell following Mesenchymal Stem Cells Co-culture. World Stem
Cells Congress (USA ,Florida - Orlando
,2017).(Invited
Speaker)
BOOK:
* Farhad Oubari, Roghaye
Hosseni Kia: Red Cell Membrane and
Disorders (Persian), Published in
Publications research Center of Iranian Blood transfusion Organization.
Teaching Course:
1. Hematology in Students of BSc laboratory Science (Department of
laboratory Science, Islamic Azad
University, Borujerd Branch, Borujerd
Iran).
2. Hematology & Blood Bankig in Students of BSc laboratory Science (Department
of laboratory Sciences, Para medical
Faculty, Kermanshah University of Medical Sciences, Kermanshah, Iran)
Researches in hands
1.
Evaluation of Multidrug Resistant Protein -1 genes expression rate in
hematopoietic stem cells derived cord blood in from concurrent culture of
hematopoietic stem cells and placenta derived mesenchymal stem cells in
presence of FLT3-L
2. The effect of quercetin supplementation on Total Antioxidant Capacity,
IL-6 and gene Expression of SREBP in nonalcoholic fatty liver disease:A
randomized, double-blind, clinical trial.
3. Effects of L-carnitine supplementation on gene
Expression of PPARα, CPT1 and ACOX and some of inflammatory factors
in patients with coronary artery disease: A randomized clinical trial.
4. Comparison
of the umbilical cord and bone marrow
CD34 + cells expansion in co-culture
with mesenchymal stem cells isolated from the placenta and bone marrow in the
presence of FLT3-L and assessment of the
differentiation potency of osteocytic, adipocytic and adipocytic mesenchymal stem cells isolated from placenta
and bone marrow.
5.Evaluation
of TSGA10 Gene in Hela Cancerous Cells
and Determination of Pattern of miRNA 200 and 214 in Angiogenesis.
6. Comparison of the Inhibitory Effect of STMN1 using the RNAi on Expansion ,Viability and Migration in
Human Cancerous Cells.
7.Role
of TSGA10 in Autophagy of Cervical Cancer Cells.
8.Study
of TSGA10 Gene Expression in Acute Myeloblastic Leukemia and Determination of
Pattern of miRNA221/222 in AML Patients.
9.The
Effect of Quercein Supplementation on Liver Enzymes,Inflammatory Indices, Lipid
Profile , and Body Composition Accompanied by Colori Control in Non Alcohlic
Fatty Liver Disease:A Randomised , Double Blind Pilot Study(Adviser) .
Language Score:
Type Score Date
MCHE(MSRT) 61 22/06/2012-22/06/2014
Lecture background;
1. Giving a lecture in the fifth
International &10th National Congress on Quality Improvement in Clinical Laboratory,
Tehran-Iran( April 23-26,2012).
2.Giving a lecture in the sixth
International Iranian Congress Laboratory
& Clinic, Tehran- Iran(Accepted first article as a lecture)( 12-14
February 2014).
3.Giving a lecture in the sixth
International Iranian Congress Laboratory
& Clinic, Tehran- Iran(Accepted second article as a lecture)( 12-14 February 2014).
4. Lecturing in blood bank (ABO
& Rh groups , Ab identification and
Screening Ab) in Assembly
hall in Kermanshah University of Medical Sciences ,Kermanshah – Iran(28 February
2009).
5. Lecturing in transmitted disease through
water and food in Kermanshah University of Medical Sciences, Kermanshah- Iran
(25 July 2007).
6.Giving a lecture in Apheresis and Hemovigilance in Kermanshah University of
Medical Sciences , Kermanshah – Iran(9 June 2014).
7. Lecturing in one – day workshop in laboratory diagnosis of
Tuberculosis,Kermanshah University of Medical Sciences, Kermanshah –Iran (9
July 2008).
8. Giving a lecture in International
Congress of Blood Diseases and Clinical
Administration , Yasuj – Iran 2015(11-14 May). .
Certificate in
participating in internal
seminars and Congress:
1. The Fifth International
&10th National Congress on Quality Improvement in Clinical Laboratory,
Tehran-Iran( April 23-26,2012).
2. The Second International &7th
National Congress on Quality Improvement
in Clinical Laboratory, Tehran-Iran( April 23-26,2009).
3. The First International
&6th National Congress on Quality Improvement in
Clinical Laboratory,
Tehran-Iran(16 February 2008).
4.Participating
certificate in Hematology workshop, Tehran-Iran
(23-26 April 2009).
5. Participating certificate in
Diagnosis of Blood Malignancy workshop, Tehran-Iran(16 February
2008).
6. Participating certificate in
Peripheral Blood Smear workshop, Tehran-Iran(16 February 2008).
7. One – day workshop in the blood
bank in Hamadan University of medical sciences , Hamadan-Iran(1 June 2009 ).
8.Certificate of perspective
course of the new employees in Kermanshah-Iran(18 March 2007).
9.Certificate of participation in
blood bank as a lecture in the system of
blood groups in Kermanshah University of Medical Sciences, Kermanshah –Iran(28
February 2009 ).
10.Certificate of participation in
blood bank ( Screening Ab & Ab Identification), Kermanshah University of
Medical Sciences, Kermanshah – Iran(28 February 2009).
11. Provience workshop in laboratory
diagnosis of Transmitted
disease through food (Salmonella ,
Shigella, Staph and Escherichia ), Kermanshah University of
Medical Sciences, Kermanshah- Iran(25 July 2007).
12. One – day
conference in Hematology , Kermanshah University of Medical Sciences ,
Kermanshah-Iran(26 February 2007).
13. One – day conference in
Experiments of urine Biochemistry, Kermanshah University of Medical Sciences,
Kermanshah – Iran( 3 March 2007).
14. One – day conference in the
approaches and techniques in Immunology, Kermanshah University of Medical
Sciences, Kermanshah – Iran (13 January 2007).
15. One – day workshop in
Blood Bank (Products of Cell and Plasma & Cross match , Quality
Control of equipments
of Blood transporter ,...)Kermanshah – Iran (4 August
2008).
16. One – day workshop in
laboratory diagnosis of Tuberculosis, Kermanshah University of Medical
Sciences, Kermanshah –Iran (9 July 2008).
17. One – day
educational workshop in laboratory diagnosis of transmitted disease through
Food , Tehran-Iran(12 February 2007).
18. Certificate of participating
in 6th International Congress in Lab and Clinic, Tehran- Iran (12-14
February 2014).
Education Background :
1. BSc Average(14.99 from
20) & Graduated in 2005.
2. MSc Average (17.16 from 20)
& Graduated in 2013.
3. Job experience in all medical
lab wards and Research sectors (1999-2016).
4. Work as a head expert from 2007
to 2009.
5. Selected as a Pathology and blood Transfusion
committee chairman & Responsible for quality control from 2007- 2009.
6.Selected as a referee of
research projects in Medical Biology Research Center,Kermansh University
of Medical Sceinces.
7.Selecte as referee two Journal (Babol and
Kermanshah):
A:Journal of Kermanshah University of Medical
Sciences.
B: Journal of Babol University of Medical
Sciences
Interests:
1. Hematopoietic and
Mesenchymal Cell Biology
2. Umbilical Cord Blood Stem cell
(Differentiation and Expansion)
3. Bone Marrow Transplantation
4. Cell Culture and
Differentiation
5. Methods of Molecular in
Diagnosis of non Hematogical ( such as Cancers) and Hematological Malignancies ( Such as Leukemia , Lymphoma,…)
6. Isolation &Expansion and Differentiation
Hematopoietic Stem cell
7.Isolation &Expansion and Differentiation
Mesenchymal Stem cells
8. Immunophenotyping of Leukemia and Solid Tumors
9.Epigenetic and Molecular Hematology
10. Immunohistochemistry of Malignancies
11. Hematopoesis & Coagulation and Blood Banking (Immunohematology)
12.Cancer and Leukemia Stem Cell
13. Inducible Progenitor Stem Cell (iPS)
14. MicroRNA
Referees :
1.
Dr. Mahin Nikougoftar Zarif
*Assistant professor , Blood Transfusion Research
Center, High Institute for Research
and Education in Transfusion Medicine,
Tehran – Iran.
E-
mail: Nikougoftar @
ibto.ir
2.Dr Kamran
Mansouri
*Assistant
professor of Molecular
Medicine,Kermanshah University of Medical Sciences,Kermanshah-Iran.
E-mail:kmansouri@kums.ac.ir
3-
Dr. Habibollah Golafshan
*Assistant
professor of Hematology and blood Banking, Shiraz University of Medical
Sciences, Shiraz- Iran.
E- mail: golafshanh@yahoo.com
4. Dr . Naser Amirizadeh
*Associated professor , Blood
Transfusion Research Center , High Institute for Research and Education In
Transfusion Medicine, Tehran-Iran.
E-Mail: n. amirizadeh @ ibto . ir